Coronavirus Vaccine Side Effects: Can severe reactions with the first dose mean your second dose side-effects will be milder?

Coronavirus Vaccine Side Effects: Can severe reactions with the first dose mean your second dose side-effects will be milder?


Yes and no. While experts continue to evaluate and look into the potential protection and shortcomings of different coronavirus vaccines, it is yet to be fully determined whether side-effects with different doses act up differently.

Not only does the answer largely depends on the vaccine you get (for example, second dose side-effects are a bit less harsh with Covishield, while on the stronger side with some other vaccines), the intensity of your side-effects, ergo, with the second dose could also be dependent on your individual response. While the findings are based on case studies, there is no scientific evidence to support the same yet.

However, there’s may also be a psychological aspect to it, which can determine how you may ‘less strongly’ react to vaccines. If a person happens to get severe reactions, for example, the first time around, maybe more prepared and aware, or be more tolerant to the intensity of side-effects. In such a scenario with a past history of severe side-effects, mild reactions can be expected the second time around.



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